Analisi Della Relazione Genotipo Fenotipo Con Algoritmi Di Machine Learning BOLOGNA

Analisi Della Relazione Genotipo Fenotipo Con Algoritmi Di Machine Learning
Bologna
Emilia Romagna, BOLOGNA

Organisation/Company: ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA - DIPARTIMENTO DI INGEGNERIA DELL'ENERGIA ELETTRICA E DELL'INFORMAZIONE "GUGLIELMO MARCONI"Research Field: Engineering » Biomedical engineeringResearcher Profile: Recognised Researcher (R2), Leading Researcher (R4), First Stage Researcher (R1), Established Researcher (R3)Country: ItalyApplication Deadline: 31 Mar 2025 - 23:59 (UTC)Type of Contract: To be definedJob Status: Not ApplicableIs the job funded through the EU Research Framework Programme?

Not funded by a EU programmeIs the Job related to staff position within a Research Infrastructure?

NoOffer DescriptionThe use of Machine Learning methods for the analysis of the genotype-phenotype relation is currently hindered by two main problems: (1) the size of the datasets compared to the high dimensionality of the genetic input features; (2) the interpretability of the results obtained in medical/biological terms.

To try to mitigate both problems, the use of neural networks that incorporate prior biological information into their architecture will be tested.

In this way, it will be possible to simultaneously reduce the number of parameters to be estimated in the training phase and to define latent features that are directly linked to known biological items.

This approach has the potential to make the information extracted from genetic data more easily adoptable in clinical practice. Eligibility of fellowsCountry/ies of residence: AllNationality/ies: #J-18808-Ljbffr