Marie Sklodowska-Curie Actions Postdoctoral Fellowships Napoli

Marie Sklodowska-Curie Actions Postdoctoral Fellowships
Napoli
Campania, Napoli

Organisation / Company: Stazione Zoologica Anton Dohrn Napoli Department: Ecosustainable Marine Biotechnology Laboratory Is the Hosting related to staff position within a Research Infrastructure? No I am pleased to offer a postdoctoral position in my lab in the Eco-sustainable Marine Biotechnology (BlueBio) department of the Stazione Zoologica Anton Dohrn in Naples. The topic of the project will be the investigation of the role of lipid-derived secondary metabolites in diatoms. Special focus will be on prostaglandins, PUFA-derived molecules well characterized in animals as hormone-like molecules involved in many physiological and pathological processes. The project aims to understand their physiological and ecological role in diatoms and other planktonic organisms. Other secondary metabolites and pathways known to be prostaglandin targets will also be considered. The project will start focusing on two main model species of the lab, Skeletonema marinoi and Thalassiosira rotula , but will then be extended to other species holding the pathway. Techniques: gDNA and RNA sequencing; bioinformatic and data mining tools; microalgae culture technique and chemical extraction; biochemistry and molecular biology techniques for gene expression and functional analysis. The goal will be to assess, among different species, strains, and organisms, the differences in the prostaglandin pathway composition and expression; the type and quantity of prostaglandin molecules synthesized; the properties of the main enzyme in the pathway, COX; and its role inside and outside the cells. Naples is a vibrant city in the south of Italy, full of contradictions, sun, and lovely people. The department is situated by the sea inside the beautiful gardens named "Molosiglio" in the city center. It is an appendix of the historical building situated not too far from us, inside the old real gardens on the city seaside. The department is in a renewed building furnished with new instrumentation bought with one of the last big government funding. The main topic of BlueBio researchers is the identification of marine microorganisms, microalgae, and bacteria, and secondary metabolites useful for biotech applications in pharmaceutical, nutraceutical, cosmeceutical, and bioremediation fields. J-18808-Ljbffr