Mrna/Lnp Process Development Scientist
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mRNA/LNP Process Development Scientist, Monza Client: Thermo Fisher Scientific
Location: Monza
Job Category: Other
EU work permit required: Yes
Job Reference: 756a86b263cd
Job Views: 12
Posted: 15. 02. 2025
Expiry Date: 01. 04. 2025
Job Description: Participate in multi-disciplinary matrix teams on sophisticated projects and lead problem-solving and lessons-learned activities.
Design and implement experimental plans, analyze in-process data and write and review high-quality reports.
Develop strong customer relationships through technical interactions.
Lead activities in the area of mRNA/LNP expertise.
Provide solutions to identify process risks, issues, and problems.
Contribute to improving departmental processes and implementing innovative technologies.
Demonstrate flexibility to support activities within the department.
Qualifications A Master's Degree in life science, Chemical, Biological, or Process Engineering, or equivalent experience, with 5+ years of confirmed experience in the Biopharmaceutical industry, preferably in a PD role.
Alternatively, a PhD in Biochemistry, Chemistry, Chemical Engineering, Biological Engineering, or related scientific subject areas, or equivalent experience, with +2 years of relevant post-doctoral or industrial experience.
Key Requirements Experience with biomolecule purification techniques such as HPLC/FPLC chromatography (including affinity, ion exchange, hydrophobic interactions, and size exclusion), tangential flow filtration (TFF), and other filtration techniques.
Knowledge of technology transfer and GMP manufacturing.
Implementation of DoE studies & high-throughput screening for purification processes.
Understanding in vitro transcription (IVT) critical process parameters, reaction optimization, and scale-up.
Experience in manufacturing large mRNA molecules, including self-amplifying and circular RNAs.
Understanding the mRNA-LNP encapsulation process scale-up and execution of relevant associated analytical methods.
Proven track record of efficiently working in a fast-paced and multifaceted environment.
Thermo Fisher Scientific is an Equal Opportunity Employer.
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