Production And Management Of Multiomic Data From Individuals With Diabetic Cardiomyopathy Lazio

Production And Management Of Multiomic Data From Individuals With Diabetic Cardiomyopathy
Roma
Lazio, Lazio

Organisation / Company: Università degli Studi di Torino

Research Field: Medical sciences

Researcher Profile: Recognised Researcher (R2), Leading Researcher (R4), First Stage Researcher (R1), Established Researcher (R3)

Country: Italy

Application Deadline: 27 Jan 2025 - 13:00 (UTC)

Type of Contract: To be defined

Job Status: Not Applicable

Funding: Not funded by a EU programme

Research Infrastructure: No

Offer Description: The aim of the CARDIATEAM project is the identification of OMIC biomarkers to assess the uniqueness of diabetic cardiomyopathy (DCM), its development, and progression.

Biomarkers include expression profiles of plasma Extracellular vesicles (EVs)-derived small non-coding RNAs (sncRNAs); the DNA methylation levels in blood; and the expression levels of messenger RNA (mRNA) in blood.

The present project's activity is based on the creation of a deeply phenotyped cohort of healthy and affected individuals to collect clinical and genetic data.

This approach will allow the exploitation of a large and well-documented dataset to identify specific genetic and epigenetic correlations, to understand the molecular mechanisms underlying diabetic cardiomyopathy, in order to identify new biomarkers that could improve diagnosis, monitoring, and potentially the development of targeted therapies for this condition.

Eligibility of fellows: All

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