Research Associate At The Elettra Nanoinnovation Laboratory trieste

Research Associate At The Elettra Nanoinnovation Laboratory
Trieste
Friuli Venezia Giulia, trieste

Organisation/Company: ELETTRA - SINCROTRONE TRIESTE S. C. P. A.

Department: HR

Research Field: Physics » Applied physics

Researcher Profile: Recognised Researcher (R2)

Positions: PhD Positions

Country: Italy

Application Deadline: 19 Jan 2025 - 23:00 (Europe/Rome)

Type of Contract: Temporary

Job Status: Full-time

Hours Per Week: 40

Offer Starting Date: 3 Mar 2025

Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description The NanoInnovation Lab (NIL) at Elettra applies advanced nanotechnologies to biology and medicine, and (bio)materials.

NIL's main activities use Atomic Force Microscopy/Fluorescence Microscopy integrated set-ups to study biological interactions at the molecular, cellular, and tissue scales, with full control of physiological parameters.

Detailed information on cell and tissue biomechanics derived from nanoindentation techniques is used to study disease progression (e. g. , cancer; neurodegenerative diseases) and to evaluate the effect of specific therapies.

The NIL has renowned expertise in biomimetic models of plasma membranes, studied with AFM, X-ray, and neutron scattering techniques, for evaluating nanovesicles (especially extracellular vesicles, EVs) and nanoparticles uptake mechanisms, in relation to membrane parameters such as order and fluidity.

The successful candidate will be introduced to the NIL environment, contributing to ongoing scientific projects and technological developments in the context of human diseases, focusing on cancer mechanobiology.

The candidate will be responsible for the experimental set-up for 2D and 3D biological samples (cells, organoids, hydrogels, and living tissues), focusing on: high-throughput nanoindentation; Atomic Force Microscopy (AFM) morphomechanical imaging; fluorescence microscopy and immunostaining protocols.

Additionally, the candidate should provide high-quality support to external users, gaining opportunities for collaborative work with national and international research groups.

Minimum Requirements: A PhD (or at least 3 years post-degree working experience) in Nanotechnology, Physics, or closely related disciplines is required, along with the following technical skills:

Proven expertise in advanced 2D and 3D cell culture techniques (including establishing, maintaining, and troubleshooting complex cellular models); Proficiency in sample preparation protocols tailored for biomechanical measurements, particularly for applications involving Chiaro Optics11 Nanoindenter and fluorescence microscopy (which includes techniques such as immunostaining, sample mounting, and data analysis); Expertise in atomic force microscopy, encompassing both imaging and sample preparation for nanoscale characterization (including familiarity with surface roughness analysis and adhesion force measurements).

Working experience with extracellular vesicles (EVs) and nanoparticles, including their isolation/synthesis, characterization, and application in biomedical research, would be considered a plus.

Excellent oral and written communication skills in English are required, with the ability to clearly present research findings and prepare scientific publications.

The candidate should possess good time management skills, a good attitude to interact with collaborators and users, and work as part of a multi-disciplinary team.

Languages: ENGLISH Level Good

Research Field: Physics » Other

Years of Research Experience: 1 - 4

Additional Information - Insurance covering accidents outside of the workplace;

- Paid holiday periods (approximately 5 weeks/year)

The deadline for the submission of the application is January 19, 2025.

The appointment is a fixed-term contract of 12 months.

The salary will be commensurate with previous experience and qualifications of the candidate.

Applications should include a full curriculum vitae signed by the applicant (preferably using the European Curriculum Vitae Format in PDF), with the names and contact information (including electronic mail) of at least two professional references.

The interviews may be held via video conferencing.

The ranking of eligible candidates resulting from this selection procedure may be used for additional appointments within the following 24 months.

Permanent employees of Elettra Sincrotrone Trieste S. C. p. A.

and employees or former employees of any Italian Public Entity who have exercised authority over Elettra Sincrotrone Trieste S. C. p. A.

or have negotiated with Elettra Sincrotrone Trieste S. C. p. A.

within the last three years will be excluded from the present selection procedure, in accordance with the provisions of article 21 of the Italian legislative decree no.

39/2013 and in conjunction with article 53 (subsection16ter) of Italian legislative decree no.

165/2001.

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