Research Associate At The Elettra Nanoinnovation Laboratory trieste

Research Associate At The Elettra Nanoinnovation Laboratory
Trieste
Friuli Venezia Giulia, trieste

Organisation/Company: ELETTRA - SINCROTRONE TRIESTE S. C. P. A.

Department: HR

Research Field: Physics » Applied physics

Researcher Profile: Recognised Researcher (R2)

Positions: PhD Positions

Country: Italy

Application Deadline: 19 Jan 2025 - 23:00 (Europe/Rome)

Type of Contract: Temporary

Job Status: Full-time

Hours Per Week: 40

Offer Starting Date: 3 Mar 2025

Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description The NanoInnovation Lab (NIL) at Elettra applies advanced nanotechnologies to biology and medicine, and (bio)materials.

NIL's main activities use Atomic Force Microscopy/Fluorescence Microscopy integrated set-ups to study biological interactions at the molecular, cellular and tissue scales, with full control of physiological parameters.

Detailed information on cell and tissue biomechanics derived from nanoindentation techniques are used to study disease progression (e. g. , cancer; neurodegenerative diseases) and to evaluate the effect of specific therapies.

The NIL has renown expertise on biomimetic models of plasma membranes, synergistically studied with AFM, X-ray and neutron scattering techniques, for the evaluation of nanovesicles (in particular extracellular vesicles, EVs) and nanoparticles uptake mechanisms, in relation to membrane parameters such as order and fluidity.

The successful candidate will contribute to ongoing scientific projects and technological developments in the context of human diseases, focusing on cancer mechanobiology.

The candidate will be responsible for the experimental set-up for 2D and 3D biological samples (cells, organoids, hydrogels, and living tissues), focusing on: high-throughput nanoindentation; Atomic Force Microscopy (AFM) morphomechanical imaging; fluorescence microscopy and immunostaining protocols.

The candidate should provide high-quality support to external users, gaining opportunities for collaborative work with national and international research groups.

Minimum Requirements A PhD (or at least 3 years post-degree working experience) in Nanotechnology, Physics, or closely related disciplines is required, along with the following technical skills:

Proven expertise in advanced 2D and 3D cell culture techniques (including establishing, maintaining, and troubleshooting complex cellular models).

Proficiency in sample preparation protocols tailored for biomechanical measurements, particularly for applications involving Chiaro Optics11 Nanoindenter and fluorescence microscopy (including immunostaining, sample mounting, and data analysis).

Expertise in atomic force microscopy, encompassing both imaging and sample preparation for nanoscale characterization (including familiarity with surface roughness analysis and adhesion force measurements).

Experience with extracellular vesicles (EVs) and nanoparticles, including their isolation/synthesis, characterization, and application in biomedical research, would be considered a plus.

Excellent oral and written communication skills in English are required, with the ability to clearly present research findings and prepare scientific publications.

The candidate should possess good time management skills, a collaborative attitude, and the ability to work as part of a multi-disciplinary team.

Additional Information Insurance covering accidents outside of the workplace.

Paid holiday periods (approximately 5 weeks/year).

The deadline for application submission is January 19, 2025.

The appointment is a fixed term contract of 12 months; salary will be commensurate with experience and qualifications.

Applications should include a full curriculum vitae signed by the applicant (preferably using the European Curriculum Vitae Format in PDF), along with the names and contact information (including email) of at least two professional references.

Interviews may be held via video conferencing.

The ranking of eligible candidates from this selection procedure may be used for additional appointments within the following 24 months.

Permanent employees of Elettra Sincrotrone Trieste S. C. p. A.

and employees or former employees of any Italian Public Entity who have exercised authority over Elettra Sincrotrone Trieste S. C. p. A.

or negotiated with Elettra - Sincrotrone Trieste S. C. p. A.

within the last three years will be excluded from this selection procedure, in accordance with the provisions of Italian legislative decree no.

39/2013 and Italian legislative decree no.

165/2001.

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