Research Fellow - Human Inherited Neuropathies Unit Milano

Research Fellow - Human Inherited Neuropathies Unit
Milano
Lombardia, Milano

IRCCS San Raffaele Scientific Institute in Milan is looking for a Pre-doctoral Research Fellow to join the Human Inherited Neuropathy Unit, led by Prof. Alessandra Bolino.

The research fellow will contribute to a preclinical gene therapy project based on AAV (Adeno-associated viral vector) delivery aimed at preventing very severe forms of demyelinating neuropathies with infantile onset in human. The fellow will work on a highly translational project in the San Raffaele campus, which provides the unique opportunity to conjugate clinical and basic research. Our laboratory collaborates with the Department of Neurology of the Hospital and participates to established national and international clinical networks on these diseases.

**Main activities**:

AAV vector cloning

Primary cell transduction

AAV9 delivery in vivo in animal models of CMT

Vector biodistribution by real time PCR analyses (VGCN)

Quantitative mRNA analysis

Biochemical analyses (biomarker analysis)

Immunohistochemistry on tissues

Morphological analyses of the peripheral and central nervous system

Behavioral studies

**Who we are looking for**:

Ability to work in team; research planning and organization, and communication skills are required

**Work details**:

**Type of contract**: collaboration full time

Immediately available

**Place of work**: IRCCS San Raffaele Hospital, Via Olgettina, number 60 - Milan (Italy)

At San Raffaele Scientific Institute, a world-renowned center of excellence for clinical and scientific activities, we believe that considering diversity and promoting an open and inclusive environment is crucial to our success. We are committed to ensure that equal employment opportunities are provided and based on merit without regard to age, religion, sex, disability, medical condition, sexual orientation, cultural and social backgrounds, gender identity or expression, national or ethnic origin, or any other legally recognized status entitled to protection under applicable laws. We offer attractive conditions and rewards appropriate to an internationally competitive research organization.