Senior Technician Lazio

Senior Technician
Roma
Lazio, Lazio

IRBM is a scientific contract research organization (CRO) that stands at the forefront of drug discovery, leveraging a single, unified research facility, located in Pomezia (Rome), Italy, to accelerate team-based breakthroughs and improve efficiencies from initial concept to pre-clinical candidate.

With a history of contributing to several approved drugs, and its own internal pipeline of oncology and other therapeutic assets, IRBM is powered by deep collaborations and decades of expertise from leading global institutions. Our comprehensive in-house capabilities assist partners in achieving key milestones and progressing towards clinical readiness, positioning IRBM as a major player in driving innovation in the pharmaceutical and biotech fields.

Job Description We currently have an open position for a highly motivated Sr Technician – Research Associate II to join our Oncology Unit and support our drug discovery efforts. She/he will execute experiments to test biological hypotheses, identify new targets, and define the mechanism of action of new molecular entities in Oncology. The successful candidate will work at the bench and is expected to provide technical support and supervision to other laboratory members, including introduction and teaching of laboratory techniques and support on the use of lab equipment.

A collaborative attitude and ability to multitask are essential for this position. Candidates with hands-on experience with cell-based assays and cell biology will be given priority.

Required qualifications: Master's degree in biology, Biochemistry, Biotechnology, or other biological science areaMinimum 2 years of postgraduate research experience with an in-depth knowledge of cancer biology and cell-based assaysMust have broad experience in cell biology and tissue culture techniquesExperience with standard molecular biology and biochemical techniques (e. g. , cloning, nucleic acid and protein isolation from human and animal tissue samples, PCR/qPCR, and Western blot)Experience with relevant experimental techniques to modulate gene expression, such as CRISPR, lentiviral transduction, RNAi, shRNA etc. Experience in bacterial transformation and restriction enzyme analysis. Excellent organizational and communication skillsProficiency in IT Tools: MS Office Software (Word, Outlook, Excel, PowerPoint), GraphPad Prism (or similar) for data analysisAbility to multitask with emphasis on accuracy and attention to detailFlexible, proactive, efficient, and able to work independently with a problem-solving attitudeStrong team player, high-energy and positive personalityWorking knowledge of English is mandatory. 2+ years of experience in a biotech/pharma company with expertise in drug discovery would be a strong assetExperience establishing and maintaining primary cell lines and organoidsExperience in screening small molecule ligands in microplate-based assay formats to drive Structure-Activity Relationship on purified protein using manual and automated systemsDevelop and perform cell-based assay enzymatic (determine enzyme activity and kinetics) and substrate binding assays independently or with other team members as instructedDuring the job interview, we will evaluate candidates' experience and the job offer will be commensurate.

We thank all applicants for their interest; candidates selected for interviews will be contacted.

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