Trainee Post-Lauream In Biological Sciences/ Biotechnology For The Identificatio... Bolzano

Trainee Post-Lauream In Biological Sciences/ Biotechnology For The Identificatio...
Bolzano
Trentino Alto Adige, Bolzano

Institute for Biomedicine The Institute for Biomedicine, located at Bolzano's NOI Techpark, is a key component of Eurac Research, dedicated to improving health through precision prevention research.

This interdisciplinary effort seeks to predict, slow or preempt illness progression by understanding genetic, biological, environmental, and lifestyle factors.

Utilizing a decade-long population study in collaboration with the South Tyrolean Healthcare Service, the institute offers access to extensive data and biological materials suitable for such research.

With a focus on neurological, cardiovascular, and metabolic health, the team employs state-of-the-art labs and innovative management to span the full translational research cycle, from data generation to potential clinical application.

In its focus area "Mitochondrial function and neuronal disease modelling" the Translational Genomics group is looking for a Trainee post lauream to work on mitochondrial targets for Parkinson's disease (PD).

Specifically, the team investigates genes and pathways that contribute to the pathological processes of PD by disrupting mitochondrial function.

Using appropriate neuronal models that include iPSC-derived neurons grown in 2D and 3D culture, we are assessing molecular phenotypes and testing specific targets and pathways for interventional strategies.

The selected candidate will join a project devoted to realizing a high-throughput screen for the identification and validation of novel molecular targets.

The position is open for students post lauream with a master's degree in science (cell biology, biotechnology, neuroscience or related disciplines) for a period of 10 months (graduation no more than 12 months before the start of the internship).

Tasks: The student will gain practical experience in scientific work by performing experimental work and data analysis.

Specifically, the experimental part will include:

iPSC culture Differentiation of iPSCs into 2D and 3D neuronal cultures Real time-PCR and Western blot Immunofluorescence and confocal imaging Biochemical assays Molecular cloning techniques Gene editing by CRISPR-Cas

Requirements: Molecular and cellular biology bases Experience in cell culture work as well as in basic molecular laboratory techniques Previous experience in iPSC culture and differentiation will be an advantage Good knowledge of English; knowledge of either German or Italian language is an advantage Well-developed social skills, a hands-on attitude and ability to work in a team Willing to develop new skills and explore novel ideas We offer: We offer a position for a 10-month project in the laboratory of the Institute for Biomedicine.

The beginning of the internship will be as soon as possible and will be discussed with the selected candidate.

international environment and engaged colleagues training in a broad range of cell and molecular biology techniques internship compensation How to apply:

Interested candidates should submit their application (CV, cover letter and further relevant documents) by 21. 02. 2025.



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